If you want to earn from Adsense, you must make your ads noticeable. Adsense performed many researches about what colors perform better on different type of ads and the answer is - it all depends on your website design colors.

There are mainly two types of designs:

• Light designs (with light backgrounds)
• Dark designs (with dark backgrounds)

Usually it's not hard to classify your design by these categories. For example blogalike.com has light design and webcodingeasy.com has dark design.

Then there are two types of ads. Ones are mixed with your main content (they are inside or between paragraphs) and others are adjacent to content, for example after the content, or on the left side under navigation, top ads etc.

Now how your ads might interact with your design? Advertisements might blend with your design, complement it or contrast it.

What does it mean?

• Blend - well usually it means that background and borders of ads match your website background color. And you can use your website's default link and text colors for your ad link and text colors (But that's not mandatory, a little change might emphasize your ads a bit).
• Contrast - here you'll have completely opposite colors of what you use for your websites. So if your website uses dark colors, you can use light colors for your ads. Same applies to text and links
• Complement - So you know the place where your add will be, and instead of taking same background color for your ads background and borders, you use a different color, which also appears on your website, for example in menu or header, or footer, but doesn't match background color of a place where advertisement will appear

So main question is, which color interaction with design to use on which advertisements?

Here are Google Adsense suggestions, which actually work pretty well:

All this information I got from: What color palettes are most successful?, which link I've found by following Google Adsense on twitter.